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Stem cell transplant types12/15/2023 ![]() Other treatments are often considered before transplant. Your healthcare team can help you consider the risks and benefits of this treatment and recommend if a transplant is right for you. Your age and other health conditions may make a stem cell transplant too dangerous. Autologous stem cell transplants are slightly more common than allogeneic stem cell transplants. The goal of the transplant is to help repair the damage done to your bone marrow and replace the blood cells that were destroyed by the higher doses of chemotherapy or radiation.īut a stem cell transplant is not the right choice for everyone with ALL. The two types are allogeneic, which uses donated stem cells, and autologous, which uses your own healthy stem cells. To counter this, a stem cell transplant will infuse (transplant) stems cells from your donor into your body. Higher doses of chemotherapy and radiation can be used to destroy the leukemia cells that are still in your body, but they can damage or destroy your bone marrow in the process. ![]() Standard doses of chemotherapy don't always bring about a remission. If the leukemia did not fully respond to treatment (called refractory ALL) and only a partial remission was ever reached during the first complete remission, depending on prognosis and risk of ALL returning (called relapsed ALL)Īfter the leukemia relapses if another complete, or sometimes partial, remission is reached.You may be offered a stem cell transplant to treat ALL: Some people with acute lymphoblastic leukemia (ALL) will have a stem cell transplant. This complex treatment has many risks, and it must be done in a special transplant centre or hospital. Healthy stem cells are then given to replace the ones in the bone marrow that were killed. Sometimes radiation therapy to the entire body (called total body irradiation, or TBI) is also used. This includes both healthy cells and cancer cells. It uses chemotherapy at very high doses to kill all of the cells in the bone marrow. Stem cells are made in the bone marrow.Ī stem cell transplant replaces stem cells when stem cells or the bone marrow are damaged. For example, all our blood cells develop from blood stem cells. Stem cells are basic cells that develop into different types of cells that have different jobs.
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